[Effect of glaucocalyxin A on level of Th1/Th2 type cytokines in mice]

Autor:	Zi-jun, Chen, Yun-sen, Li, Ji-yan, Zhou, Zheng-tao, Wang
Rok vydání:	2006
Předmět:	Male Mice Inbred BALB C Plants Medicinal Tumor Necrosis Factor-alpha Th1 Cells Interferon-gamma Mice Th2 Cells Isodon Animals Cytokines Interleukin-2 Female Interleukin-4 Interleukin-5 Diterpenes Kaurane Drugs Chinese Herbal
Zdroj:	Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 31(15)
ISSN:	1001-5302
Popis:	To research the effect of glaucocalyxin A (GLA) on the level of Th1/Th2 type cytokines in mice.By using flow cytometer with CBA software to detect Th1/Th2 type cytokines.GLA had insighificant inhibitory effects on Th1 and Th2 cytokines (IL-2, IFN-gamma,TNF-alpha, IL-4 and IL-5) induced by ConA, in which more potential on cytokines from Th1 than those of from Th2 were displayed. However, GLA could produce inhibition on IL-2, IFN-gamma and TNF-alpha and acceleration on IL-4 and IL-5.Immunosuppressive effect of GLA is related to the influence the level of Th1/Th2 type cytokines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::fe0591b4947f3ae863c82a07a72c9c72 https://pubmed.ncbi.nlm.nih.gov/17048571 Zobrazit plný text záznamu