Autor: |
Xin, Qian, Yan, Tian, Xinxin, Luo, Jingmiao, Pan, Suya, Deng, Yike, Huang, Qifeng, Fu, Zhining, Xia |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Se pu = Chinese journal of chromatography. 38(10) |
ISSN: |
1000-8713 |
Popis: |
Capillary electrophoresis (CE) shows enormous potential for application in new drug research and development. Because of the aqueous medium employed as the running buffer in CE, drug screening can be carried out in an environment similar to that in physiological testing media. Drug screening methods based on CE are different from other instrumental measurements in vitro. CE can not only sustain the biological activity of the screened molecules and ligands, but also help evaluate the interactions between the receptors and the ligands. Based on these interactions, some important pharmacological parameters related to drug screening, such as the association constant |
Databáze: |
OpenAIRE |
Externí odkaz: |
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