| Autor: |
E, Delaval, S, Andriamanantsara, N, Freund, J, Bastin, J P, Geloso |
| Rok vydání: |
1985 |
| Předmět: |
|
| Zdroj: |
Journal of developmental physiology. 7(6) |
| ISSN: |
0141-9846 |
| Popis: |
Developmental changes in the activities of two enzymes catalysing transfer of fatty acid across the mitochondrial membrane (carnitine-palmitoyl-transferase and carnitine-acetyl-transferase) were studied in the kidneys of developing rats from late fetal life to 10 days post-partum and were compared to cortical adult value. The activities of carnitine-palmitoyl-transferase and carnitine-acetyl-transferase increased after birth to reach a maximal value on day 5. Thereafter both activities decreased to reach adult cortical value. The cytochrome c oxidase activity (index of mitochondrial activity) increases continuously from late fetal age to adult. In kidneys of fetuses from starved mothers the carnitine-palmitoyl-transferase activity is higher than that of controls while carnitine-acetyl-transferase activity is not changed. In postmature fetuses (23 days post-coïtum) carnitine-palmitoyl-transferase activity is the same as in 21 days post-coïtum old fetuses. These results are discussed in relation to variations in nutritional and hormonal changes occurring during the perinatal period. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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