Bile acid metabolites control T

Autor: Saiyu, Hang, Donggi, Paik, Lina, Yao, Eunha, Kim, Jamma, Trinath, Jingping, Lu, Soyoung, Ha, Brandon N, Nelson, Samantha P, Kelly, Lin, Wu, Ye, Zheng, Randy S, Longman, Fraydoon, Rastinejad, A Sloan, Devlin, Michael R, Krout, Michael A, Fischbach, Dan R, Littman, Jun R, Huh
Rok vydání: 2018
Předmět:
Zdroj: Nature. 576(7785)
ISSN: 1476-4687
Popis: Bile acids are abundant in the mammalian gut, where they undergo bacteria-mediated transformation to generate a large pool of bioactive molecules. Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is unknown whether they affect adaptive immune cells such as T helper cells that express IL-17a (T
Databáze: OpenAIRE