[Intraocular infection with herpesviruses and antiviral immunity in patients with age-related macular degeneration]

Autor:	A Sh, Mukhamed'ianova, R A, Aznabaev, L F, Aznabaeva
Rok vydání:	2008
Předmět:	Male Cytomegalovirus Eye Infections Viral Herpes Simplex Middle Aged Antibodies Viral Polymerase Chain Reaction Severity of Illness Index Macular Degeneration Tears Cytomegalovirus Infections DNA Viral Lens Crystalline Humans Simplexvirus Female Aged Follow-Up Studies
Zdroj:	Vestnik oftalmologii. 124(2)
ISSN:	0042-465X
Popis:	Polymerase chain reaction revealed Herpesviridae (Herpes simplex, Cytomegalovirus) in the lens substance in 46 patients operated on for age-related cataract. Thirty-two patients of them had age-related macular degeneration. Herpes simplex was found in 6 (18.8%) of the patients with age-related macular degeneration. At the same time there were signs of lacrimal fluid antiviral immunity imbalance with decreased IFN-gamma and TNF-alpha and increased IFN-alpha. The authors consider it advisable to perform antivirus treatment in patients with the above abnormality, preventing the active forms of herpetic infection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::fdaa7cad454b8a5a53b5df5ae4b1e0a8 https://pubmed.ncbi.nlm.nih.gov/18488471 Zobrazit plný text záznamu