Construction of centrosomes and spindle poles by molecular motor-driven assembly of protein particles

Autor:	W, Zimmerman, S J, Doxsey
Rok vydání:	2001
Předmět:	Centrosome Models Molecular Molecular Motor Proteins Dyneins Nuclear Proteins Biological Transport Cell Cycle Proteins CHO Cells Spindle Apparatus Autoantigens Microtubules Cricetinae Animals Antigens
Zdroj:	Traffic (Copenhagen, Denmark). 1(12)
ISSN:	1398-9219
Popis:	Centrosomes and other microtubule organizing centers are the largest non-membranous organelles in most cells. This morphologically diverse class of organelles shares a common ability to nucleate and organize microtubules in interphase and participates in the formation of mitotic spindles during cell division. This review summarizes recent evidence suggesting that assembly of centrosomes and mitotic spindle poles require transport of large protein particles along microtubules by the molecular motor cytoplasmic dynein.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::fda546bc5c7702750c7564087e4b5197 https://pubmed.ncbi.nlm.nih.gov/11208082 Zobrazit plný text záznamu Plný text