The influence of low-molecular fraction from cord blood (below 5 kDa) on functional and biochemical parameters of cells in vitro
| Autor: | A K, Gulevsky, N N, Moisieieva, O L, Gorina, J S, Akhatova, A A, Lavrik, A V, Trifonova |
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| Rok vydání: | 2015 |
| Předmět: |
Phagocytes
Swine Primary Cell Culture Epithelial Cells Mesenchymal Stem Cells Heme Chemical Fractionation Fibroblasts Alkaline Phosphatase Embryo Mammalian Fetal Blood Cell Line Iodoacetic Acid Rats Biological Factors Glucose Phagocytosis Cricetinae Leukocytes Mononuclear Animals Humans Cattle Cell Proliferation |
| Zdroj: | Ukrainian biochemical journal. 86(6) |
| ISSN: | 2409-4943 |
| Popis: | The influence of a low-molecular fraction (below 5 kDa) from the cattle cord blood (CBF) on functional activity of phagocytes, human embryonic fibroblasts, mesenchymal stromal cells and BHK-21 clone 13/04 and PK-15 cells was studied. The low-molecular fraction added to culture medium increases the growth rate of cell cultures. The incubation of leukoconcentrate in the CBF-containing medium results in an increase in phagocytic indices ofneutrophils in the presence of a phagocytosis inhibitor--sodium iodoacetate, leading to a significant increase in intracellular glucose content and alkaline phosphatase activity as compared to the control and the reference drug Actovegin®. |
| Databáze: | OpenAIRE |
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