| Autor: |
Qin-Lei, Gao, Ping-Xia, Guo, Qi, Luo, Hui, Yan, Yong-Xian, Cheng |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Natural product communications. 10(12) |
| ISSN: |
1934-578X |
| Popis: |
Petchienes A-E (1-5), five new meroterpenoids, were isolated from the fruiting bodies of Ganoderma petchii. Their structures, including absolute configurations, were elucidated by means of spectroscopic and computational methods. Compound 4 was isolated as a racemic mixture, which was finally purified by chiral HPLC to yield individual (-) and (+)-antipodes. Biological evaluation showed that compounds 2 and (-)-4 could increase intracellular free calcium concentration at 10 μM in HEK-293 cells. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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