Qualitative assessment of selective blockade of M(4)-cholinoreceptors in the whole organism

Autor:	S G, Dagaev, A B, Kosmachev, N M, Libman, L G, Kubarskaya, A V, Khrabrova, V I, Sanotskii, O A, Fil'ko, V B, Dolgo-Saburov
Rok vydání:	2003
Předmět:	Atropine Dose-Response Relationship Drug Receptor Muscarinic M4 Pilocarpine Animals Muscarinic Antagonists Motor Activity Muscarinic Agonists Rats Trihexyphenidyl Tropanes
Zdroj:	Bulletin of experimental biology and medicine. 135(5)
ISSN:	0007-4888
Popis:	Quantitative assessment of selective blockade of M4-subtype muscarinic receptors was performed by the number of pilocarpine-induced movements of lower jaw in rats. Three antagonists (atropine, cyclodol, and glipin) were used in the experiments. Glipin produced the most potent blockade of M4 receptors in the whole organism compared to other test antagonist.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::fd42e462101d33c7eb15ed8299f90162 https://pubmed.ncbi.nlm.nih.gov/12910282 Zobrazit plný text záznamu Full text from SpringerLink