Evaluation of antioxidant activity and toxicity of sulfur- or selenium-containing 4-(arylchalcogenyl)-1

Autor: Daniela, Hartwig de Oliveira, Fernanda Severo Sabedra, Sousa, Paloma Taborda, Birmann, Ana Paula, Pesarico, Diego, Alves, Raquel Guimarães, Jacob, Lucielli, Savegnago
Rok vydání: 2020
Předmět:
Zdroj: Canadian journal of physiology and pharmacology. 98(7)
ISSN: 1205-7541
Popis: Pyrazoles represent a significant class of heterocyclic compounds that exhibit pharmacological properties. The present study aimed to investigate the antioxidant potential of pyrazol derivative compounds in brain of mice in vitro and the effect of pyrazol derivative compounds in the oxidative damage and toxicity parameters in mouse brain and plasma of mice. The compounds tested were 3,5-dimethyl-1-phenyl-4-(phenylselanyl)-1
Databáze: OpenAIRE