Pattern of cerebral hyperperfusion in Alzheimer’s disease and amnestic mild cognitive impairment using voxel-based analysis of 3D arterial spin-labeling imaging: initial experience
| Autor: | Ding, Bei, Ling, Hua-wei, Zhang, Yong, Huang, Juan, Zhang, Huan, Wang, Tao, Yan, Fu Hua |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
Neuroimaging arterial spin labeling Magnetic Resonance Imaging Temporal Lobe Frontal Lobe amnestic mild cognitive impairment Alzheimer Disease Case-Control Studies Cerebrovascular Circulation mental disorders Humans perfusion image Cognitive Dysfunction Female Spin Labels Alzheimer’s disease Original Research Aged |
| Zdroj: | Clinical Interventions in Aging |
| ISSN: | 1178-1998 1176-9092 |
| Popis: | Purpose A three-dimensional (3D) continuous pulse arterial spin labeling (ASL) technique was used to investigate cerebral blood flow (CBF) changes in patients with Alzheimer’s disease (AD), amnestic mild cognitive impairment (aMCI), and age- and sex-matched healthy controls. Materials and methods Three groups were recruited for comparison, 24 AD patients, 17 MCI patients, and 21 age- and sex-matched control subjects. Three-dimensional ASL scans covering the entire brain were acquired with a 3.0 T magnetic resonance scanner. Spatial processing was performed with statistical parametric mapping 8. A second-level one-way analysis of variance analysis (threshold at P |
| Databáze: | OpenAIRE |
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