Pulmonary non-caseating granuloma in Waldenström macroglobulinemia

Autor: Ryuki, Fukuda, Hiroshi, Kawada, Yoshiaki, Ogawa, Hidetaka, Yanagi, Seiichiro, Kojima, Tetsuya, Urano, Ito, Chie, Makoto, Onizuka, Satomi, Fukagawa, Masako, Shimada, Rikio, Suzuki, Atsushi, Takagi, Tomomitsu, Hotta
Rok vydání: 2005
Předmět:
Zdroj: The Tokai journal of experimental and clinical medicine. 30(2)
ISSN: 0385-0005
Popis: Lung involvement is rare in Waldenström macroglobulinemia (WM). We encountered a male patient with WM who complained of breathlessness. Chest X-ray revealed diffuse infiltrative shadow throughout the both lungs. Transbronchial biopsy showed infiltration of atypical plasmacytoid lymphocytes and non-caseating granuloma. We treated the patients with fludarabine phosphate, and both his symptom and X-ray findings were then improved. To our knowledge, this is the first case showing non-caseating granuloma with lung involvement of WM. We discuss a mechanism of non-caseating granuloma formation in this case.
Databáze: OpenAIRE