Association between cannabis and psychiatric hospitalization

Autor: C D, Schubart, M P M, Boks, E J, Breetvelt, W A, van Gastel, R H H, Groenwold, R A, Ophoff, I E C, Sommer, R S, Kahn
Rok vydání: 2011
Předmět:
Zdroj: Acta psychiatrica Scandinavica. 123(5)
ISSN: 1600-0447
Popis: To investigate the relationship between cannabis use and mental health.A cross-sectional analysis in a sample of 17 698 individuals with a mean age of 22 years (SD: 4.2). Participants provided information on the amount and initial age of cannabis use and history of psychiatric hospitalizations through a web-based questionnaire. To quantify Δ(9) -tetrahydrocannabinol exposure, we operationalized cannabis use as the amount of money spent on cannabis per week over the last month. The odds ratio of having a history of psychiatric hospitalizations was the primary outcome measure.We found a dose-response relationship between the amount of cannabis use and the odds for psychiatric hospitalization. Adjusted odds ratios for hospitalization increased with the amount of cannabis consumed from 1.6 (95% CI: 1.1-2.3) in incidental users to 6.2 (95% CI: 4.3-8.9) in heavy users (€25/week). Our data suggested that concomitant drug use was an intermediate factor. Exposure to cannabis before the age of 12 years was found to carry a 4.8 (95% CI: 2.9-7.8) times increased odds for past psychiatric hospitalizations.We conclude that early and heavy uses of cannabis are each and independently associated with poor mental health in its users.
Databáze: OpenAIRE
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