Comparison between dynamic gadoxetate-enhanced MRI and
| Autor: | F, Rassam, T, Zhang, K P, Cieslak, C, Lavini, J, Stoker, R J, Bennink, T M, van Gulik, L J, van Vliet, J H, Runge, F M, Vos |
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| Rok vydání: | 2018 |
| Předmět: |
Gadolinium DTPA
Male Tomography Emission-Computed Single-Photon Liver Diseases Pilot Projects Middle Aged Magnetic Resonance Imaging Hepatobiliary-Pancreas Liver Liver Function Tests Gadolinium ethoxybenzyl DTPA Hepatectomy Humans Technetium Tc 99m mebrofenin Female Prospective Studies Radiopharmaceuticals Radionuclide Imaging Aged |
| Zdroj: | European Radiology |
| ISSN: | 1432-1084 |
| Popis: | Objectives To compare Gd-EOB-DTPA dynamic hepatocyte-specific contrast-enhanced MRI (DHCE-MRI) with 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) as quantitative liver function tests for the preoperative assessment of patients undergoing liver resection. Methods Patients undergoing liver surgery and preoperative assessment of future remnant liver (FRL) function using 99mTc-mebrofenin HBS were included. Patients underwent DHCE-MRI. Total liver uptake function was calculated for both modalities: mebrofenin uptake rate (MUR) and Ki respectively. The FRL was delineated with both SPECT-CT and MRI to calculate the functional share. Blood samples were taken to assess biochemical liver parameters. Results A total of 20 patients were included. The HBS-derived MUR and the DHCE-MRI-derived mean Ki correlated strongly for both total and FRL function (Pearson r = 0.70, p = 0.001 and r = 0.89, p |
| Databáze: | OpenAIRE |
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