[Effects of clopheline on impulse activity of neurons in the midbrain and dorsal horn of the spinal cord]

Autor: A A, Zaĭtsev, S M, Butkhuzi, V V, Kolchin, B T, Moroz, Z A, Sakvarelidze
Rok vydání: 1989
Předmět:
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny. 108(8)
ISSN: 0365-9615
Popis: Clophelin (1-5 mg/kg) suppresses spinal dorsal horn neuronal nociceptive responses but does not change their touch stimuli reactions in unanesthetized curarized cats. This effect is steady to naloxone (1 mg/kg), yohimbine (5 mg/kg) and removal by prazosin (1 mg/kg). Clophelin depresses nociceptive responses of the central gray matter neurones which generalized pain impulses in the supraspinal structures.
Databáze: OpenAIRE