[Intravascular malignant B-cell lymphomatosis with renal glomerular involvement: a case]

Autor: C, Charasse, R, Boulahrouz, S, Le Moal, J, Bousser, A, Pasquiou, P, Le Cacheux, K S, Ang, P, Simon, M P, Ramée
Jazyk: francouzština
Rok vydání: 1998
Předmět:
Zdroj: Nephrologie. 19(4)
ISSN: 0250-4960
Popis: We report a case of intravascular malignant lymphomatosis observed in a 71 year-old male and characterised by the presence of a proteinuria in relation to the specific intraglomerular localisation. This malignant lymphoma, usually of the B phenotype, is rare and affects predominantly the central nervous system and the skin. Neoplastic cells home selectively to endothelium. Histological renal infiltration is frequent but a glomerular localisation, with proteinuria, is rare. The mechanism whereby lymphocytes home to endothelium cells is unclear but it could be related to the expression of lymphocyte-endothelium adhesion molecules. When present the nephrotic syndrome is associated with minimal change disease.
Databáze: OpenAIRE