The analgesic evaluation of gabapentin for arthroscopy
| Autor: | Huang, Feiri, Yang, Zhifang, Su, Zhongliang, Gao, Xiaosheng |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pain
Postoperative gabapentin meta-analysis Placebos Arthroscopy Treatment Outcome pain management randomized controlled trials Postoperative Nausea and Vomiting Humans Pain Management Gabapentin Systematic Review and Meta-Analysis Research Article arthroscopy Pain Measurement Randomized Controlled Trials as Topic |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | Introduction: The efficacy of gabapentin for pain management of arthroscopy remains controversial. We conduct a systematic review and meta-analysis to explore the influence of gabapentin versus placebo on the postoperative pain intensity of arthroscopy. Methods: We search PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases through April 2020 for randomized controlled trials assessing the effect of gabapentin versus placebo on pain control of arthroscopy. This meta-analysis is performed using the random-effect model. Results: Five randomized controlled trials are included in the meta-analysis. Overall, compared with control group for arthroscopy, gabapentin remarkably decreases pain scores at 24 hour (standard mean difference [SMD]=-0.68; 95% confidence interval [CI]=-1.15 to -0.02; P = .21), analgesic consumption (SMD = -18.24; 95% CI=-24.61 to -11.88; P |
| Databáze: | OpenAIRE |
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