[Antibiotic consumption at Antananarivo University Hospital: prevalence and strategic challenges]

Autor: Fidiniaina Mamy, Randriatsarafara, Jaona, Ralamboson, Rivo, Rakotoarivelo, Antso, Raherinandrasana, Rado, Andrianasolo
Jazyk: francouzština
Rok vydání: 2015
Předmět:
Zdroj: Sante publique (Vandoeuvre-les-Nancy, France). 27(2)
ISSN: 0995-3914
Popis: Very few studies have been conducted on antibiotic consumption in Madagascar. The objective of this study was to describe antibiotic consumption in a tertiary university hospital in Antananarivo, Madagascar to more clearly define good antibiotic use strategies.A one-day prevalence survey was conducted on 5 April 2011 in the 339-bed Befelatanana Hospital with a bed occupation rate of 65.5%.The prevalence of antibiotic therapy among the 222 patients hospitalised on the day of the survey was 57.2%. Almost one half (49.6%) of patients received a combination of at least two antibiotics. The classes of antibiotics most commonly prescribed were beta-lactam antibiotics (55.3%), imidazoles (14.9%), aminoglycosides (14.9%), quinolones (7.9%) and macrolides with 7% of prescriptions. Penicillins accounted for 55.5% of all beta-lactam antibiotic prescriptions, followed by third-generation cephalosporins. Children under the age of 14 years (p0.019) and patients with invasive devices (p10(-6)) received more antibiotics. Antibiotic prescription in the Emergency Room–Intensive Care Unit was significantly higher than in the other wards (p0.01).A high rate of antibiotic use was observed in Befelatanana University Hospital. Beta-lactam antibiotics were the agents most commonly prescribed and the Emergency Room–Intensive Care Unit was the leading antibiotic prescriber. It is essential to set up a good antibiotic use policy.
Databáze: OpenAIRE