| Autor: |
Y, Yamaguchi, K, Otsuka, Y, Habu, K, Ohyama, T, Kurotsu, T, Ookawara, S, Ohkuma, T, Yamakawa, K, Suzuki |
| Rok vydání: |
2003 |
| Předmět: |
|
| Zdroj: |
Research communications in molecular pathology and pharmacology. 110(5-6) |
| ISSN: |
1078-0297 |
| Popis: |
Vgu glycoprotein (Vicia graminea lectin- or Vicia unijuga lectin-binding glycoprotein) has been reported as oncofetal antigen, which is found in many kind of tumor tissues, amniotic fluid and fetal membranes. In autoradiography with an 125I-labeled Vicia unijuga lectin (VUA) probe and an 125I-labeled Arachis hypogaea lectin (PNA, anti-T lectin) probe, seminal plasma samples of eight healthy men gave 2-7 Vgu glycoproteins without T antigen, 1-2 Vgu glycoproteins with Thomsen-Friedenreich antigen (T antigen) and 1-8 T-antigen glycoproteins, respectively. These results show that in addition to T-antigen glycoproteins, normal human seminal plasma contains Vgu glycoproteins and Vgu glycoproteins with T antigen as seminal plasma components as well as other tumor markers such as CA19-9, CA-125 and CEA. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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