| Autor: |
A M, Koriakin, N N, Epifantseva, I V, Dadyka, Ia A, Gorbatovskiĭ |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Klinicheskaia laboratornaia diagnostika. (4) |
| ISSN: |
0869-2084 |
| Popis: |
The levels of homocysteine (HC) and von Willebrand factor (VWF) as cardiovascular risk factors were studied in patients with Stage II chronic alcoholism. Forty-one men with Stage II chronic alcoholism without clinical signs of somatic and infectious diseases were examined. Their median age was 37 (range 32-40) years; the alcoholization period was 12 (range 8-17) years. Plasma HC and VWF (amount and activity) levels were determined. In 63.4% of chronic alcoholic patients, HC levels was twice as high as in the controls; in 80.6%, both the content and activity of VWF were increased. There was no correlation between the levels of HC and VWF. Vascular endothelial damage concurrent with hyperhomocysteinemia increases a cardiovascular risk in patients with Stage II chronic alcoholism. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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