Global and cardiovascular mortality and risk factors in patients under hemodialysis treatment

Autor: Fátima Aparecida A, Almeida, Felipe Carrhá, Machado, José Andrade, Moura, Armênio Costa, Guimarães
Rok vydání: 2008
Předmět:
Zdroj: Arquivos brasileiros de cardiologia. 94(2)
ISSN: 1678-4170
Popis: There is a high global and cardiovascular mortality rate among patients who need hemodialysis.To assess global and cardiovascular mortality and to identify the risk factors in patients who undergo hemodialysis.Observational, prospective study. A total of 334 patients were studied within three years.global and cardiovascular mortality. Survival was assessed through Kaplan-Meier method, and the risk variables were identified by means of bivariate and multivariate Cox regression.A total of 189 men (56.6%), aging 48.8 +/- 14.2, majority non-white (295, 88.3%) and who did finished the elementary school (211, 63.2%). Global mortality rate was 21.6%, with a 50% rate of 146-month survival; cardiovascular mortality rate was 41.7% (30/72), with a 75% rate of 141-month survival. In the bivariate analysis, the relative risk (RR) for non-cardiovascular and cardiovascular death increased when ageor =60 years old was Hbor =9.0 g/dl and fast glycemiaor =126 mg/dl. Only non-cardiovascular death with low school grade and widow, Hb11.0 g/dl, Ht33.0%, fast glycemiaor =100 mg/dl, Ca product x P42 and creatinineor =9.2 mg/dl decreased with blood pressure (BP)or =140/90 mmHg (before hemodialysis session) and Ht36%; Obit due only to cardiovascular factors increased with creatinineor =9.4 mg/dl. In the multivariate analysis, non-cardiovascular and cardiovascular RR increased with ageor =60 years old and Hb9 g/dl; cardiovascular death RR increased with glycemiaor =126 mg/dl, and non-cardiovascular death RR increased with urea removal rate in hemodialysis (Kt/V)1,2.Global and cardiovascular mortality of patients who need hemodialysis is high. Independent risk factors for non cardiovascular and cardiovascular causes of death were age60 years old and Hb9 g/dl, for cardiovascular cause of death only, was fasting blood glucoseor =126 mg/dL, and for non-cardiovascular cause of death, Kt/V1,2.
Databáze: OpenAIRE