ABCA3 lung disease in an ex 27 week preterm infant responsive to systemic glucocorticosteroids

Autor:	Jason Kg, Tan, Conor, Murray, Andre, Schultz
Rok vydání:	2015
Předmět:	Homozygote Infant Newborn Mutation Missense Infant Gestational Age Methylprednisolone Dexamethasone Treatment Outcome Humans ATP-Binding Cassette Transporters Female Lung Diseases Interstitial Glucocorticoids Infant Premature
Zdroj:	Pediatric pulmonology. 51(1)
ISSN:	1099-0496
Popis:	We present a case of an infant born at almost 28 weeks gestation, found to be homozygous for a missense mutation of ABCA3, with diffuse lung disease that has continued throughout infancy. The patient's clinical course and chest imaging was highly suggestive of diffuse lung disease of infancy, and not of chronic lung disease of prematurity. The lung disease proved to be highly responsive to systemic corticosteroids. This is a case of ABCA3 lung disease that demonstrated improvement after systemic glucocorticosteroid administration.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f97ce119cacb3c029baa2b18828010cf https://pubmed.ncbi.nlm.nih.gov/26222203 Zobrazit plný text záznamu Plný text