| Autor: |
Lenuţa, Profire, D, Pieptu, Raluca Petronela, Dumitriu, Oana, Dragostin, Cornelia, Vasile |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. 117(2) |
| ISSN: |
0048-7848 |
| Popis: |
To present the research results concerning enhanced antimicrobial and release properties of the chitosan derivative with sulfadiazine/hyaluronic acid polyelectrolyte complex (PEC) hydrogel.The PECs have been prepared from chitosan of different molecular weight, sulfadiazine chitosan derivative and sodium hyaluronate. The complex structure was assessed by FT-IR spectroscopic method and swelling capacity was followed by weighing measurements.It has been establish that chitosan derivative influenced both PEC properties and swelling capacity.Incorporation in PEC of the sulfadiazine chitosan is a new way to combine bacteriostatic effect of chitosan with that of sulfadiazine, to control properties, antimicrobial activity in the treatment of the wound. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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