| Autor: |
Ranjit, Philip, B Rush, Waller, Sandeep, Chilakala, Brittany, Graham, Nathan, Stecchi, Leah, Apalodimas, Jorden, Cunningham, Kristen, Washington, Shyam, Sathanandam |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Journal of perinatology : official journal of the California Perinatal Association. 41(1) |
| ISSN: |
1476-5543 |
| Popis: |
To describe changes in hemodynamics, respiratory support, and growth associated with transcatheter PDA closure (TCPC) in ELBW infants, stratified by postnatal age at treatment.This is an observational study of ELBW infants who underwent TCPC at ≤4 weeks (Group-1; n = 34), 4-8 weeks (Group-2; n = 33), and8 weeks of age (Group-3; n = 33). Hemodynamic assessment was performed during TCPC. Multivariate Cox-proportionate-hazard modeling was used to identify factors associated with respiratory severity score (RSS) 2 for30 days following TCPC.In comparison with Group-1, Group-3 infants had higher pulmonary vascular resistance (PVRi = 3.3 vs. 1.6 WU*mELBW infants may benefit from PDA closure within the first 4 weeks of life in order to prevent early onset pulmonary vascular disease, promote faster growth, and for quicker weaning of ventilator and oxygen support. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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