| Autor: |
D S, Bordin, A A, Masharova, S Iu, Sil'vestrova, L D, Firsova, O V, Safonova, A V, Petrakov, T S, Kozhurina, E R, Valitova, O B, Ianova |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimentalclinical gastroenterology. (9) |
| ISSN: |
1682-8658 |
| Popis: |
Was made an investigation of the effectiveness of pantoprazole (sanpraz, "SanFarma", India) at gastroesophageal reflux disease (GERD). 53 patients with GERD, including 20--with reflux esophagitis, received a daily dose of pantoprazole 40 mg to 28 days. To the 7 day of treatment heartburn was broke in 63.3%, regurgitation--in 65% of patients initially experiencing these symptoms. The 14-th day of treatment heartburn was broke in 83.7%, regurgitation--in 90%. Endoscopic remission in 28-th day of treatment was obtained in 85% of patients with reflux esophagitis. Broking of symptoms was accompanied by significant improvement in well-being and quality of life of patients. Treatment of a standard dose of pantoprazole was ineffective in 16.3% of patients. The reasons for the conservation of heartburn in 4.1% of the cases was an individual characteristics of the pharmacokinetics drug, in 12.2%--non-reflux mechanisms of symptoms in the face of mental status. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
