Specificity of genome evolution in experimental populations of

Autor: Daniel E, Deatherage, Jamie L, Kepner, Albert F, Bennett, Richard E, Lenski, Jeffrey E, Barrick
Rok vydání: 2017
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America. 114(10)
ISSN: 1091-6490
Popis: Organisms evolve and adapt via changes in their genomes that improve survival and reproduction in the context of their environment. Few experiments have examined how these genomic signatures of adaptation, which may favor mutations in certain genes or molecular pathways, vary across a set of similar environments that have both shared and distinctive characteristics. We sequenced complete genomes from 30 Escherichia coli lineages that evolved for 2,000 generations in one of five environments that differed only in the temperatures they experienced. Particular “signature” genes acquired mutations in these bacteria in response to selection imposed by specific temperature treatments. Thus, it is sometimes possible to predict aspects of the environment recently experienced by microbial populations from changes in their genome sequences.
Databáze: OpenAIRE