Patterns of X chromosome inactivation in haematopoietic cells of female carriers of X linked severe combined immunodeficiency

Autor:	R W, Hendriks, M E, Kraakman, R K, Schuurman
Rok vydání:	1993
Předmět:	Male B-Lymphocytes X Chromosome Genetic Linkage Genetic Carrier Screening Hematopoietic System T-Lymphocytes Methylation Dosage Compensation Genetic Humans Female Severe Combined Immunodeficiency Dinucleoside Phosphates Granulocytes
Zdroj:	Immunodeficiency. 4(1-4)
ISSN:	1067-795X
Popis:	We evaluated the use of methylation analysis at the DXS255 locus as a method for carrier detection in X-linked severe combined immunodeficiency (XSCID). We also investigated the variations of X inactivation patterns in several haematopoietic cell lineages of XSCID carriers, both within and between XSCID pedigrees.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f8a504f887b231821aee1e480dd6dc36 https://pubmed.ncbi.nlm.nih.gov/8167715 Zobrazit plný text záznamu