Myelopathy after intrathecal chemotherapy. A case report with unique magnetic resonance imaging changes

Autor:	D R, McLean, H M, Clink, P, Ernst, R, Coates, M Z, al Kawi, S, Bohlega, S, Omer
Rok vydání:	1994
Předmět:	Gadolinium DTPA Paraplegia Adolescent Cytarabine Contrast Media Antineoplastic Agents Pentetic Acid Precursor Cell Lymphoblastic Leukemia-Lymphoma Magnetic Resonance Imaging Spinal Cord Diseases Drug Combinations Meglumine Methotrexate Organometallic Compounds Humans Female Injections Spinal
Zdroj:	Cancer. 73(12)
ISSN:	0008-543X
Popis:	Paraplegia caused by intrathecal chemotherapy has no known pathognomonic features and is a diagnosis of exclusion.The authors reported the clinical and neuroimaging findings in one patient with this syndrome.The patient had severe paraplegia with urinary retention and impaired pain and touch sensation below T-10 with sparing of proprioception and vibration sense. Magnetic resonance imaging (MRI) scan showed diminished intensity throughout the central cervical spinal cord. Post-gadopentetate dimeglumine enhancement was scattered throughout the cervical spinal cord and in two areas of the dorsal spinal cord. Axial views of the cervical spinal cord showed that this enhancement was limited to the lateral columns.The MRI in myelopathy due to intrathecal chemotherapy may show a unique pattern of postgadopentetate dimeglumine enhancement limited to the lateral columns of the spinal cord. However, two recently encountered patients with the same syndrome did not show similar changes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f801128b9432d7ed716a2d2dc014192b https://pubmed.ncbi.nlm.nih.gov/7850723 Zobrazit plný text záznamu Plný text