Paediatric immunisation and chemoprophylaxis in a Ugandan sickle cell disease clinic
| Autor: | Chung-Jen, Chen, Sabrina, Bakeera-Kitaka, Ezekiel, Mupere, Philip, Kasirye, Deogratias, Munube, Richard, Idro, Heather, Hume, Betsy, Pfeffer, Philip, LaRussa, Nancy S, Green |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Immunization Programs Incidence Vaccination Infant Anemia Sickle Cell Chemoprevention Risk Assessment Pneumococcal Infections Article Malaria Pneumococcal Vaccines Cross-Sectional Studies Child Preschool Communicable Disease Control Ambulatory Care Humans Female Uganda Child Developing Countries Retrospective Studies |
| Zdroj: | J Paediatr Child Health |
| ISSN: | 1440-1754 |
| Popis: | We aimed to assess the receipt of recommended care for young children with sickle cell disease (SCD) in a central SCD clinic in Kampala Uganda, focusing on standard vaccination and antibacterial and antimalarial prophylaxis.A cross-sectional assessment of immunisation status and timeliness and prescribed antibacterial and antimalarial prophylaxis was performed in a sample with SCD aged ≤71 months in Mulago Hospital SCD Clinic. Government-issued immunisation cards and clinic-issued visit records for prescribed prophylaxis were reviewed.Vaccinations were documented by immunisation cards in 104 patients, mean age 31.7 months (range 3-70 months). Only 48 (46.2%) received all doses of each of the four recommended vaccine types, including pneumococcal 10-valent conjugate vaccine (pneumococcal conjugate vaccine (PCV)-10), which became available in 2014. Vaccination completion was associated with younger age and, for polio, maternal employment. PCV-10 series was completed in 54.8% of the sample and in 18.2% of those aged 48-71 months. Of children completing all vaccination types, an average 68.8% were immunised on time, defined as60 days beyond the recommended age. Only 17 (13.5%) children were both fully and timely vaccinated. In an overlapping sample of 147 children, with a mean age of 38.4 months (4-70 months), 81.6% had ≥1 documented prescription for penicillin and/or antimalarial prophylaxis.Standardised vaccination and antibacterial and antimalarial protective measures for young children at this central SCD clinic were incomplete, especially PCV-10 for age ≥24 months, and often late. Child age, but not general maternal demographics, were associated with vaccination and chemoprophylaxis. Clinic-based oversight may improve timely uptake of these preventative measures. |
| Databáze: | OpenAIRE |
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