[The morphologic variants of KSHV/HHV 8-associated lymphoproliferations]

Autor: C, Loddenkemper, T, Longerich, T, Schneider, I, Anagnostopoulos, H D, Foss, P, Schirmacher, H, Stein
Jazyk: němčina
Rok vydání: 2006
Předmět:
Zdroj: Der Pathologe. 28(1)
ISSN: 0172-8113
Popis: KSHV/HHV 8 infection is associated with primary effusion lymphoma, multicentric Castleman disease (MCD) and MCD-associated plasmablastic lymphoma. We report the case of an HIV-infected male with Kaposi sarcoma, MCD in the lymph node and development of a KSHV/HHV 8-associated plasmablastic lymphoma in the liver. Immunohistochemistry revealed an HHV 8 infection of plasmablasts showing cytoplasmic IgM/lambda expression. To the best of our knowledge, liver infiltration by a MCD-associated HHV 8 positive plasmablastic lymphoma has not been documented previously. The differential diagnosis is discussed.
Databáze: OpenAIRE