[Left ventricular filling behavior in stress-induced myocardial ischemia--correlation between Doppler echocardiography determined transmitral flow profile and pulmonary capillary pressure]

Autor: H, Völler, C, Spielberg, K, Schröder, B, Breitkreuz, A, Uhrig, R, Dissmann, H, Dingerkus, R, Schröder
Jazyk: němčina
Rok vydání: 1994
Předmět:
Zdroj: Zeitschrift fur Kardiologie. 83(4)
ISSN: 0300-5860
Popis: The way Doppler-derived transmitral filling patterns are changed because of myocardial ischemia is controversial. Furthermore, the influence of the filling pressure has not been investigated sufficiently. To evaluate the relationship between transmitral flow profile and pulmonary capillary wedge pressure (PC), 35 patients with exercise-induced myocardial ischemia were examined. Both Doppler-derived transmitral filling patterns and PC were determined simultaneously at rest and during three stages of supine bicycle exercise. Patients were subdivided into two groups according to the hemodynamic response (group 1 = PC20 mm Hg; n = 10, and group 2 = PCor = 20 mm Hg; n = 25). The correlation between PC and transmitral filling patterns was low at rest for all patients, but improved at maximal workload, particularly for the atrial contribution (r = -0.79), as well as the ratio of maximal and integrated early to late diastolic flow velocities (rE/A = 0.74; rEi/Ai = 0.72). Both groups revealed different flow profiles in regard to the hemodynamic response. While group 1 showed an E/A-ratio1, an E/A-ratio1 was registered in group 2 (0.9 m/s versus 1.61 m/s; p0.001). Exercise-induced myocardial ischemia lead to different Doppler-derived transmitral flow patterns with regard to the filling pressure. The relationship to the pulmonary capillary wedge pressure is so close that an E/A-ratio1 is a reliable parameter to predict a filling pressure20 mm Hg.
Databáze: OpenAIRE