Post-neurosurgical meningitis; gram negative bacilli vs. gram positive cocci

Autor: Mehdi, Zeinalizadeh, Roya, Yazdani, Mohammad Mehdi, Feizabadi, Maryam, Shadkam, Arash, Seifi, Seyed Ali, Dehghan Manshadi, Alireza, Abdollahi, Mohammadreza, Salehi
Rok vydání: 2021
Zdroj: Caspian journal of internal medicine. 13(3)
ISSN: 2008-6164
Popis: Post-neurosurgical meningitis is a significant cause of mortality and morbidity. In this study we aimed to compare the differences of clinical, laboratory features and outcomes between the post-neurosurgical meningitis caused by gram-negative bacilli (GNB) and gram-positive cocci (GPC).Cases of post-neurosurgical meningitis (with positive CSF culture) were included. After classifying patients as GNB and GPC groups, clinical and paraclinical data were compared.Out of 2667 neurosurgical patients, CSF culture was positive in 45 patients. 25 (54.3%) were GNB, 19 (41.3%) GPC. The most common microorganisms wereThe GNB antibiotic coverage should be designed more carefully in post-neurosurgical meningitis especially in patients with recent corticosteroid therapy and elevated ESR and procalcitonin.
Databáze: OpenAIRE