[Fundamental aspects of oncogenesis]
| Autor: | Julie, Lemaire, Romain, Larrue, Michael, Perrais, Christelle, Cauffiez, Nicolas, Pottier |
|---|---|
| Jazyk: | francouzština |
| Rok vydání: | 2020 |
| Předmět: |
Inflammation
Transcriptional Activation Neovascularization Pathologic Carcinogenesis Apoptosis Oncogenes Environment Neoplastic Cells Circulating Genomic Instability Neoplasms Mutation Disease Progression Tumor Microenvironment Humans Genes Tumor Suppressor Neoplasm Invasiveness Gene Silencing Neoplasm Metastasis Precancerous Conditions Carcinoma in Situ Cell Proliferation |
| Zdroj: | Bulletin du cancer. 107(11) |
| ISSN: | 1769-6917 |
| Popis: | Tumorigenesis has traditionally been considered as a multi-step process involving the activation of oncogenes as well as the inactivation of tumor suppressor genes. However, the mechanisms driving cancer initiation and progression are not restricted to molecular alterations and instead should be viewed as a complex process that interfaces with the entire organism. This didactic review provides an integrated and global view of the key fundamental principles of cancer development. |
| Databáze: | OpenAIRE |
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