[Bortezomib-induced acute neutrophilic dermatosis]

Autor: A, Tanguy-Schmidt, M, Avenel-Audran, A, Croué, S, Lissandre, M, Dib, M, Zidane-Marinnes, M-P, Moles, M, Hunault-Berger
Jazyk: francouzština
Rok vydání: 2008
Předmět:
Zdroj: Annales de dermatologie et de venereologie. 136(5)
ISSN: 0151-9638
Popis: Bortezomid is a potent proteasome inhibitor used in patients with relapsing or refractory multiple myeloma and provides a 35% response with a median duration of response of 12 months. Numerous adverse effects are known, mainly comprising haematological and neurological complications. A wide variety of cutaneous complications have also been described in 10 to 20% of patients.We report a case of bortezomib-induced Sweet syndrome. The diagnostic criteria required for drug-induced Sweet syndrome were present.The importance of this description is that this induced Sweet syndrome may not necessarily require cessation of bortezomid since administration of corticosteroids prevents its recurrence.
Databáze: OpenAIRE