Dimethanesulphonate esters in receptor mapping studies. 2. Antitumour activities of alkyl and alkoxy dimethanesulphonates substituted on a benzene nucleus

Autor:	J A, Hadfield, B W, Fox, R, Caffrey
Rok vydání:	1992
Předmět:	Structure-Activity Relationship Drug Design Receptors Drug Animals Antineoplastic Agents Benzene Methyl Methanesulfonate Rats
Zdroj:	Anti-cancer drug design. 7(3)
ISSN:	0266-9536
Popis:	The antitumour activities of 15 novel aromatic dimethanesulphonate esters were studied. Several alkyl and alkoxy compounds have shown good antitumour activity whilst similar isomers have proved ineffective as antitumour agents. These differences in activity have been correlated with the length of the sidechain substituents and their relative flexibilities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f6f97aa0bee908d4fa05afcacd3787b7 https://pubmed.ncbi.nlm.nih.gov/1610483 Zobrazit plný text záznamu