Opiate receptor avidity in the thalamus is sexually dimorphic in the elderly

Autor:	R M, Cohen, R E, Carson, T, Sunderland
Rok vydání:	2000
Předmět:	Male Analysis of Variance Sex Factors Thalamus Alzheimer Disease Receptors Opioid Humans Regression Analysis Female Middle Aged Naltrexone Aged Tomography Emission-Computed
Zdroj:	Synapse (New York, N.Y.). 38(2)
ISSN:	0887-4476
Popis:	Opiate receptor avidity (B(')(max)/K(D)), was measured in the subcortex of nine females (five healthy subjects, four Alzheimer patients) and 15 males (seven healthy subjects, eight Alzheimer patients), 51-75 years of age, with the opiate receptor antagonist 6-deoxy-6-beta-[(18)F]fluoronaltrexone (cyclofoxy, CF) and a positron emission tomograph. CF avidity was 27.5% less in the thalamus of healthy women compared to healthy men and 48.5% less in Alzheimer disease female patients compared to male patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f6aee9c020b35354b24f8a6bd240caaa https://pubmed.ncbi.nlm.nih.gov/11018796 Zobrazit plný text záznamu Plný text