Evidence for sltA1 as a salt-sensitive allele of the arginase gene (agaA) in the ascomycete Aspergillus nidulans

Autor:	D J, Clement, M S, Stanley, N A, Attwell, N J, Clipson, D A, Fincham, P, Hooley
Rok vydání:	1996
Předmět:	Arginase Protoplasts Genes Fungal Drug Resistance Microbial Sodium Chloride Arginine Aspergillus nidulans Potassium Chloride Meiosis Phenotype Transformation Genetic Chlorides Mutagenesis Alleles Crosses Genetic
Zdroj:	Current genetics. 29(5)
ISSN:	0172-8083
Popis:	Strains of Aspergillus nidulans carrying the sltA1 mutation, conferring sensitivity to KCl and NaCl, also showed an arginine-sensitive phenotype whereby concentrations of the L-amino acid at or above 10 mM were toxic to growth. Sexual progeny of a cross between a sltA1 mutant and a wild-type strain showed a co-segregation of salt and arginine sensitivity. Similarly, revertants to salt tolerance showed a loss of arginine sensitivity as did sltA1 strains that were transformed with a cosmid carrying the putative sltA1+ wild-type allele. In addition, arginine sensitivity could be relieved by L-ornithine. It is suggested that sltA1 is a salt-sensitive allele of the arginase gene (agaA).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f67c997bc6e9add7fb2b3ab57672619d https://pubmed.ncbi.nlm.nih.gov/8625426 Zobrazit plný text záznamu Full text from SpringerLink