[Gastric cancer: probability assessment after lymph node-negative staging and its consequences]

Autor: Juan Manuel, Miralles-Tena, Javier, Escrig-Sos, David, Martínez-Ramos, Vicente, Angel-Yepes, Carmen, Villegas-Cánovas, Vicente, Senent-Vizcaíno, José Luis, Salvador-Sanchís
Rok vydání: 2006
Předmět:
Zdroj: Cirugia espanola. 80(1)
ISSN: 0009-739X
Popis: To provide an approach to calculating the probability of error after lymph node-negative staging in gastric cancer.Retrospective data of 75 gastric resections for cancer were used to calculate the probability of error in general, according to T staging of the TNM classification (6th edition) and according to the type of lymphadenectomy performed. A modification of a procedure based on Bayes' theorem was used.For all tumors, at least 11 negative lymph nodes were required to ensure a true pN0. Two lymph nodes were required for T1 tumors, 11 for T2 tumors, and 14 for T3 tumors. A greater number of lymph nodes were required for a D2 lymphadenectomy than for a D1 lymphadenectomy. However, in D2 lymphadenectomy, pN0 stages were almost always reliable, while in D1 lymphadenectomy 24% of stagings were unreliable.The present study describes a simple and reproducible mathematical model that could help surgeons to determine the accuracy of lymph node-negative stages in a substantial group of patients with gastric cancer.
Databáze: OpenAIRE