[Two cases of stage IV gastric cancer who underwent total gastrectomy and achieved long-term survival by sequential chemotherapy]
| Autor: | Hiroaki, Tomimatsu, Tatsuya, Nakano |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
Antimetabolites Antineoplastic Paclitaxel Adenocarcinoma Middle Aged Irinotecan Antineoplastic Agents Phytogenic Combined Modality Therapy Drug Combinations Oxonic Acid Methotrexate Gastrectomy Stomach Neoplasms Antineoplastic Combined Chemotherapy Protocols Humans Camptothecin Female Fluorouracil Immunosuppressive Agents Tegafur |
| Zdroj: | Gan to kagaku ryoho. Cancerchemotherapy. 34(13) |
| ISSN: | 0385-0684 |
| Popis: | We describe two patients, who suffered from Stage IV gastric poorly differentiated adenocarcinoma and underwent palliative total gastrectomy, were treated by sequential chemotherapy and achieved long term-survival. The first patient was a 55-year-old male with peritoneal dissemination. After total gastrectomy, he was treated with methotrexate-5-fluorouracil (MTX/5-FU) sequential therapy for 5 months, S-1 single-agent therapy for 4 years and weekly paclitaxel (PTX) therapy for 9 months. He is being treated with irinotecan (CPT-11) therapy as an outpatient now, and has achieved 5 year 8-month survival. The second patient was a 60-year-old female. We observed unresectable metastases around the pancreas, aorta, and transverse mesocolon. She was treated with S-1 single-agent therapy for 1 year 10 months, MTX/5-FU sequential therapy for 9 months. She is now receiving weekly PTX therapy for 3 months as an outpatient and has achieved 2 year 11-month survival. |
| Databáze: | OpenAIRE |
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