Autor: |
Blossom, Akagbosu, Zakieh, Tayyebi, Gayathri, Shibu, Yoselin A, Paucar Iza, Deeksha, Deep, Yollanda Franco, Parisotto, Logan, Fisher, H Amalia, Pasolli, Valentin, Thevin, Rasa, Elmentaite, Maximilian, Knott, Saskia, Hemmers, Lorenz, Jahn, Christin, Friedrich, Jacob, Verter, Zhong-Min, Wang, Marcel, van den Brink, Georg, Gasteiger, Thomas G P, Grünewald, Julien C, Marie, Christina, Leslie, Alexander Y, Rudensky, Chrysothemis C, Brown |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Nature. 610(7933) |
ISSN: |
1476-4687 |
Popis: |
Establishing and maintaining tolerance to self-antigens or innocuous foreign antigens is vital for the preservation of organismal health. Within the thymus, medullary thymic epithelial cells (mTECs) expressing autoimmune regulator (AIRE) have a critical role in self-tolerance through deletion of autoreactive T cells and promotion of thymic regulatory T (T |
Databáze: |
OpenAIRE |
Externí odkaz: |
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