[Atrial fibrillation and QT prolongation due to proton pump inhibitor-induced hypomagnesemia]

Autor:	N, Noirclerc, C, Delfanne, A, Dompnier
Jazyk:	francouzština
Rok vydání:	2020
Předmět:	Male Electrocardiography Long QT Syndrome Hypocalcemia Atrial Fibrillation Humans Drug Synergism Magnesium Proton Pump Inhibitors Diuretics Magnesium Deficiency Aged
Zdroj:	Annales de cardiologie et d'angeiologie. 69(4)
ISSN:	1768-3181
Popis:	Proton pump inhibitors are widely prescribed but their long-term use can expose patients to adverse effects. Some of these are not very well known, including hypomagnesemia. Hypomagnesemia can be manifested by cardiac complications such as supraventricular arrhythmia or QT prolongation, increasing the risk of torsade de pointe. We present a case of atrial fibrillation triggered by severe hypomagnesemia secondary to proton pump inhibitor use and exacerbated by thiazide diuretic treatment. Conversion to sinus rhythm showed a prolonged corrected QT interval. We approach the pathophysiology and the electrophysiologic effects of hypomagnesemia.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f6346a58cc01f6a29c2933fe47263eb9 https://pubmed.ncbi.nlm.nih.gov/32800318 Zobrazit plný text záznamu Full Text from ScienceDirect