Chemoprophylaxis of multidrug-resistant tuberculous infection in HIV-uninfected individuals using ciprofloxacin and pyrazinamide. A decision analysis

Autor:	J P, Stevens, T M, Daniel
Rok vydání:	1995
Předmět:	Adult Health Personnel Decision Trees Pyrazinamide Sensitivity and Specificity Decision Support Techniques Occupational Diseases Ciprofloxacin HIV Seronegativity Tuberculosis Multidrug-Resistant Humans Tuberculosis Pulmonary Software Probability
Zdroj:	Chest. 108(3)
ISSN:	0012-3692
Popis:	To evaluate the use of ciprofloxacin and pyrazinamide for the prophylaxis of individuals infected with multiply drug-resistant strains of Mycobacterium tuberculosis.Decision analysis, using software (SMLTREE). Probabilities based on published studies, with sensitivity analysis for each probability.Health-care workers infected with multidrug-resistant strains of M tuberculosis.Prophylaxis with ciprofloxacin and pyrazinamide.We calculated the utilities of taking or not taking prophylaxis with ciprofloxacin and pyrazinamide. The decision analysis favored the use of ciprofloxacin-pyrazinamide prophylaxis by a small margin.Ciprofloxacin-pyrazinamide prophylaxis should be considered for health-care workers infected with multiply drug-resistant M tuberculosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f628de7fcce7c15a78f807dcc355c4b3 https://pubmed.ncbi.nlm.nih.gov/7656621 Zobrazit plný text záznamu