[Interaction of C60 fullerene-polyvinylpyrrolidone complex and brain Aβ(1-42)-peptide in vitro]

Autor: A G, Bobylev, Iu V, Shatalin, I M, Vikhliantsev, L G, Bobyleva, S V, Gudkov, Z A, Podlubnaia
Rok vydání: 2015
Předmět:
Zdroj: Biofizika. 59(5)
ISSN: 0006-3029
Popis: Using a spectrophotometric method changes occurring in solution containing brain Aβ(1-42)-peptide, fullerene C60, and polyvinylpyrrolidone were analyzed. Using the Bent-French method relative binding constants of fullerene C60 with Aβ(1-42)-peptide and polyvinylpyrrolidone with Aβ(1-42)- peptide were determined. These data suggest that Aβ(1-42)-peptide interacting with the C60 fullerene-polyvinylpyrrolidone complex partially displaces polyvinylpyrrolidone and generates a new three molecular compound.
Databáze: OpenAIRE