Timing of Cytosine Methylation on Newly Synthesized RNA by Electron Microscopy

Autor:	Lorena, Zannino, Stella, Siciliani, Marco, Biggiogera
Rok vydání:	2020
Předmět:	Staining and Labeling Transcription Genetic Immunohistochemistry Methylation Chromatin Epigenesis Genetic Cytosine Microscopy Electron 5-Methylcytosine RNA Precursors Humans RNA Polymerase II RNA Messenger RNA Processing Post-Transcriptional Uridine HeLa Cells
Zdroj:	Methods in molecular biology (Clifton, N.J.). 2175
ISSN:	1940-6029
Popis:	Increasing evidence demonstrates that RNA nucleotides undergo epigenetic modifications, such as methylation on cytosine. Although the presence of modified bases on mRNA has been proven, their molecular significance is largely undefined. We describe here a methodology to dissect the timing of modification of cytosine to 5-methylcytosine (5mC or m
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f60930af789fc4016f5e588f070b1cde https://pubmed.ncbi.nlm.nih.gov/32681492 Zobrazit plný text záznamu