| Autor: |
D, Bielicki, M, Markiewski, M, Wielondek, M, Chosia, W, Domagała |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Polish journal of pathology : official journal of the Polish Society of Pathologists. 46(3) |
| ISSN: |
1233-9687 |
| Popis: |
Proliferative activity of epithelial tumor cells was evaluated with the use of immunohistochemistry and anti-PCNA monoclonal antibodies in alcohol fixed paraffin embedded sections of 44 colonic adenomas, including 33 tubular, 5 villous and 6 tubulovillous adenomas. The mean PCNA index was 24.7 +/- 10.9%, 24.8 +/- 6.2% and 24.8 +/- 14.0% in tubular, villous and tubulovillous adenomas respectively. In 12 tubular adenomas with dysplasia the mean PCNA index in areas with dysplasia was significantly higher (38.2 +/- 11.5%) as compared to areas without dysplasia (17.0 +/- 8.9%; p0.05). The results indicate that PCNA index of epithelial tumor cells is significantly increased in adenomas with high grade of dysplasia irrespective of histological type or size of the tumour. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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