| Autor: |
E W, Paice, A J, Tookman, A G, White |
| Rok vydání: |
1982 |
| Předmět: |
|
| Zdroj: |
European journal of rheumatology and inflammation. 5(3) |
| ISSN: |
0140-1610 |
| Popis: |
Forty-one patients with inflammatory or degenerative arthritis and a history of gastric disturbance on other non-steroid anti-inflammatory drugs, or of peptic ulceration were treated with fenbufen 600-1200 mg dialy, and followed up for 3-17 months in an open study. Twelve patients withdrew because of lack of effect of the drug on the arthritic symptoms. Four patients withdrew because of non-gastrointestinal side effects. Three patients withdrew because of continuing dyspepsia. Twenty-two patients continued on fenbufen without dyspepsia or evidence of gastro-intestinal bleeding for 3-17 months (mean 8.3 months). These results suggest that fenbufen can be tolerated by patients with a history of gastro-intestinal disturbance on other NSAIDs, and that a larger controlled study would be warranted. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
