| Autor: |
Ke, Su, Rumi, McGloin, Rochelle M, Gellatly |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
PharmacotherapyReferences. 40(6) |
| ISSN: |
1875-9114 |
| Popis: |
Torsade de pointes is a form of polymorphic ventricular tachycardia associated with heart rate-corrected QT (QTThe objective of this study was to evaluate the predictive validity (sensitivity and specificity) and likelihood ratios of the TRS in a medical ICU.This was a longitudinal, retrospective, cohort study of consecutive patients who met the inclusion criteria from October 2017 to June 2018 with a sample size of 264 patients. The sample size was derived based on the number of TRS covariates and an exploratory variable. Baseline characteristics and risk factors were documented from electronic health records. The first occurrence of QTThe sensitivity and specificity of the TRS for low-risk patients against the moderate-risk and high-risk patients were 97% (95% CI 91-99%) and 16% (95% CI 11-23%), respectively. These results corresponded to a positive likelihood ratio of 1.15 (95% CI 1.07-1.24) and a negative likelihood ratio of 0.20 (95% CI 0.06-0.65).In conclusion, the TRS showed a high sensitivity, making it useful in identifying patients at risk of developing QT |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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