| Autor: |
Mohammad Farris Iman, Leong Abdullah, Kok Leng, Tan, Suresh, Narayanan, Novline, Yuvashnee, Nelson Jeng Yeou, Chear, Darshan, Singh, Oliver, Grundmann, Jack E, Henningfield |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Clinical toxicology (Philadelphia, Pa.). 59(5) |
| ISSN: |
1556-9519 |
| Popis: |
Little is known about the cardiotoxic effects of kratom (We enrolled regular kratom users and non-kratom-using control subjects from three communities. Demographic data, clinical data, kratom use characteristics, and ECG findings were recorded. The mitragynine content of kratom juice was quantified using a validated gas chromatography-mass spectrometry (GC-MS) method.A total of 200 participants (100 kratom users and 100 control subjects) participated in this study. The prevalence of ECG abnormalities in kratom users (28%) did not differ from that of control subjects (32%). Kratom use was not associated with ECG abnormalities, except for significantly higher odds of sinus tachycardia (OR = 8.61, 95% CI = 1.06-70.17,We found no link between regular kratom use and electrocardiographic abnormalities with an estimated average daily intake of 434.28 mg of mitragynine. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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