| Autor: |
Zhao-Liang, Yu, Xuan-Hui, Liu, Hua-Shan, Liu, Jia, Ke, Yi-Feng, Zou, Wu-Teng, Cao, Jian, Xiao, Zhi-Yang, Zhou, Ping, Lan, Xiao-Jian, Wu, Xian-Rui, Wu |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Surgical endoscopy. 35(5) |
| ISSN: |
1432-2218 |
| Popis: |
The impact of pelvis on the development of anastomotic leak (AL) in rectal cancer (RC) patients who underwent anterior resection (AR) remains unclear. The aim of this study was to evaluate the impact of pelvic dimensions on the risk of AL.A total of 1058 RC patients undergoing AR from January 2013 to January 2016 were enrolled. Pelvimetric parameters were obtained using abdominopelvic computed tomography scans.Univariate analyses showed that pelvic inlet, pelvic outlet, interspinous distance, and intertuberous distance were significantly associated with the risk for AL (P 0.05). Multivariate analysis confirmed that pelvic inlet and intertuberous distance were independent risk factors for AL (P 0.05). Significant factors from multivariate analysis were assembled into the nomogram A (without pelvic dimensions) and nomogram B (with pelvic dimensions). The area under curve (AUC) of nomogram B was 0.72 (95% CI 0.67-0.77), which was better than the AUC of nomogram A (0.69, [95% CI 0.65-0.74]), but didn't reach a statistical significance (P = 0.199). Decision curve supported that nomogram B was better than nomogram A.Pelvic dimensions, specifically pelvic inlet and intertuberous distance, seemed to be independent predictors for postoperative AL in RC patients. Pelvic inlet and intertuberous distance incorporated with preoperative radiotherapy, preoperative albumin, conversion, and tumor diameter in the nomogram might provide a clinical tool for predicting AL. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink