| Autor: |
O P, Riabchikov, S P, Shmeleva, N A, Chuich, Z S, Khlystova, I I, Kalinina, E L, Rabotnikova, I S, Sibakova, G I, Gerasiuta, E V, Lobusov |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Arkhiv patologii. 57(2) |
| ISSN: |
0004-1955 |
| Popis: |
Percentage and mitotic regimen (mitotic index, mitotic phases, pathological mitosis) of hematopoietic liver cells of the embryos and foetuses (6-12 weeks of development) from females living in normal conditions (Moscow) and in polluted with radionuclides after Chernobyl accident territory of Bryansk region of Russian Federation (towns Novozybkov and Klintsy) are characterized. Moderate but statistically significant (P0.05) differences were found in the number of polychromatophilic and oxyphilic normoblasts, basophilic megaloblasts, granulocytes at various developmental stages in the study group compared to the control. No difference was observed in 1992 in the mitotic activity, total number of pathological mitoses and the percentage of binuclear cells. But the spectrum of pathological mitoses, in the contaminated zone, seems to be wider. The mitotic index and the number of cells per 1 mg of organ tissue showed two-fold increase in 1993 in the town of Novozybkov as compared to the control area. The conclusion is made that small radiation doses exert only very slight influence on hematopoiesis in human embryonic and foetal liver of 6-12 weeks of gestation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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